Pfizer and me – Best Buddies

21st March 2022


Someone once said to me that I really must despise the pharmaceutical industry. There are certainly times when this is true, and my anger with them is sharp … and hot.

But yet, and yet, I know many people who work in the industry, and they all seem nice, concerned about the world, caring. Trying to do good. The industry itself has also produced some great innovations and medications. Without which the world would be a much scarier and more unpleasant place.

In truth, I find the industry is a bit like capitalism. Both fantastic and dreadful. Which is a bit like humanity itself. Both fantastic and dreadful. Capable of the most amazing things, yet the darker side can be very dark indeed. Dr Jekyll and Mr Hyde.

To be frank, my personal problems with the pharmaceutical industry have mainly centred around cholesterol lowering. Various companies have made billions, nay tens of billions, nay hundreds of billions, pushing LDL-Cholesterol reduction with all their might.

However, I have oft sat with my head in my hands in despair at such nonsense. Pfizer with Lipitor (atorvastatin) pushed the hardest and made the most … and horribly distorted the entire world of cardiovascular disease research in so doing.

However, thirty years ago, and purely by chance, the planets Pfizer and Kendrick were in a strange alignment. Briefly, I found myself on the same side as Pfizer when it came to cardiovascular disease.

How could this possibly be so? Well, gentle reader, let me take you back to a time when Pfizer had a very different drug to promote, called Doxazocin. It was a type of blood pressure lowering agent known as an Alpha-1 blocker. It was not selling terribly well, so they were looking for other angles in an attempt to boost sales.

I should mention that this was before Pfizer had a statin. A time that you could refer to as the ‘BS’ era. (Or maybe we are now in the true BS era – discuss). Then, in the year 2000, Pfizer took over Warner Lambert, which just happened to have a statin called atorvastatin (Lipitor). Yes, Pfizer didn’t actually develop atorvastatin. They just bought out the company that did. Nifty move.

Anyway, in 1992, Pfizer was not much interested in lowering LDL-Cholesterol, as they didn’t have a statin. Which meant they had other fish to fry with their cardiovascular drugs. They were more focussed on blood pressure lowering. But their Alpha-1 blocker for this, doxazocin (Cardura) was a bit rubbish.

So, what to do? What to do indeed. What they did was to use the tried and trusted mechanisms of looking at different effects that this drug might have.

To explain, almost all drugs when they are launched are marketed for one indication, and that indication only – the thing that will make the most money. Achieving marketing approval, for any indication e.g., blood pressure lowering, costs vast sums of money. Which means that companies must keep their focus tight, to drive the drug through the clinical trials process.

However, almost all drugs will do many other things, and you cannot run separate clinical trials on them all. To long, too complex, too costly.

There may be some ‘magic bullet’ drug that hits one target, and one alone, and spares everything else. Sniper fire. However, with most of them, you select automatic, raise the gun over your head from behind a sheltering wall, close your eyes, and spray bullets vaguely towards the target. Hoping you manage to hit the thing you’re aiming at.

Just to give a few well-known examples from history. Aspirin was initially found to reduce pain, inflammation and temperature. It was later discovered it helps to prevent platelets (small blood cells) sticking together. So, it was also an anti-coagulant – it reduced the risk of blood clots forming – and thus reduced the risk of dying of a heart attack. Now, it is being used to prevent cancer.

Sildenafil (Viagra) was initially developed as a drug for angina. The rest, as they say is history. It ended up being marketed for erectile dysfunction because it had an unknown, at the time, ‘off-target effect’ that had nothing, directly to do with angina at all. Or, at least, no-one could see the connection at the time.

Thalidomide was originally developed as a sedative. It was then sold for treating colds, flu, nausea and morning sickness. As everyone now knows, it caused horrible deformities in the unborn child.

Coincidentally, it was discovered the very same mechanism that led to the terrible deformities, also meant it was pretty good at treating a whole series of different diseases, such as multiple myeloma and leprosy. It is now prescribed as Thalomid – it has many different names. But certainly not thalidomide.

Last time I bothered counting, statins had thirty-four off-target effects. These are sometimes called ‘pleiotropic’ effects. I suppose this makes them sound more scientific. I am only surprised that statins have not yet been repurposed as anti COVID19 drugs. Probably because they are all off-patent, thus cannot make vast sums of money.

In an attempt to pull all these strands together, if your drug is not selling that well, have a closer look at all the other things it may do. The off-target effects, the ‘pleiotropics’. It has already reached market, at great cost, and whilst you are not allowed advertise it for ‘off-label’ benefits i.e., benefits not studied in the clinical trials, you can hold educational meetings and produce educational booklets to promote these additional things.

You can, effectively, launch it again as ‘Cardura two point one’. Ladies and Gentlemen …. drum roll. ‘A new era in cardiovascular disease prevention has begun.’ Dun, dun, duuuuuuuuun!’

At which point you can purchase a few off the shelf cardiology opinion leaders to push Cardura two point one with great enthusiasm. Throw a few million – carefully labelled – free pens, sticky pads, and BP cuffs around as an appreciative gift to doctors. Take them to a free lunch, sorry, educational meeting. Bore them for ten minutes, then reward them with a prawn sandwich. Feed the sea-lions.

And lo it came to pass that Pfizer scrutinised Cardura in greater detail, and found that it, like aspirin, helped to stop platelets sticking together. Platelets are small cells that float around in the bloodstream and play the key role in blood clotting. They have been described as the conductors of the clotting orchestra.

If you stop platelets sticking together, you can reduce the risk of cardiovascular disease, as was discovered with aspirin. Aha! So, not only does Cardura lower blood pressure, but it also has ‘anti-coagulant’ properties. Even better, it reduced fibrinogen, and PAI-1 and increased TPa activity. These are all ‘good’ in reducing the formation and increasing the breakdown of blood clots. As Pfizer stated:

‘These recent studies suggest that doxazosin may have a range of significant antithrombotic effects in many patients…’

Unfortunately, in 1992 doctors had already been under heavy and continuous bombardment with the message that lowering cholesterol and blood pressure were, by far, the most important things you could possibly do to prevent cardiovascular disease.

Blood clotting? Well, aspirin was used, a bit. But this was mainly to help with the final event. The big blood clot that blocked a major artery. No-one was suggesting that blood clotting had anything to do with atherosclerosis itself.

After all, how can blood clotting possibly cause atherosclerotic plaques to develop? As everyone had already been told, and told, and told … and told, and then told some more, atherosclerotic plaques (the entities that gradually grow and narrow down arteries) were full of cholesterol. Not the remnants of blood clots.

Love and marriage may go together like a horse and carriage, but platelet aggregation and atherosclerotic plaques …. You certainly cannot get a rhyme out of that – go on, I challenge you. Ergo, it must be wrong.

It was certainly a big mountain to climb. ‘You know that stuff about cholesterol…. Sorry. Turns out we should have been looking at Platelets and blood clotting instead.’ Here from a booklet on Cardura in 1992:

Platelets and atherosclerosis progression

Several features of mature plaques, such as their multi-layered pattern, suggest that platelet aggregation and thrombus formation are key elements in the progression of atherosclerosis. Platelets are also known to provide a rich source of growth factors, with can stimulate plaque development.

Given the insidious nature of atherosclerosis, it is vital to consider the role of platelets and thrombosis in this process, and the serious events that may be triggered once plaques are already present.

Goodness me. Who said all this? Why, of course it was Pfizer … Pfizer, Pfizer, Pfizer.

However, they didn’t get very far with this story. Merck were hammering away with simvastatin (Zocor) and Bristol Myers Squibb were also promoting pravastatin (Pravachol) with relentless fervour. The world of cardiovascular disease prevention was moving even more firmly in the direction of cholesterol lowering and statins.

As King Cnut (Canute to you and me) once demonstrated, once the tide starts to come in, not even a king can stop it. And the statin wave was very powerful. On the basis that, if you can’t beat them, join them, Pfizer decided to ride that wave. So, they went out and bought a large part of it, then bought the surf-boards and the tinnies.

To their (money making) credit, they then rode the cholesterol wave exceptionally well. To be frank you would buy a used car from Pfizer. I don’t know how they got so brilliant at spraying bull-shit with yellow paint, to make it look like one-hundred per-cent gold bullion, but there is no doubt they are the masters of pharmaceutical marketing.

At which point the Kendrick and Pfizer, planets were no longer in alignment. We span off on different orbits. I was still slowly plodding along the ‘platelets and atherosclerosis progression’ path, trying to make sense of it all.

Pfizer, to flip my analogies, firmly jumped on the ‘all singing, all dancing’ cholesterol lowering bandwagon.’ Complete with dancing girls in fancy costumes, a brass band, champagne, hundreds of balloons – and all the key opinion leaders in cardiology singing ‘We’re in the money.’

We’re in the money

We’re in the money

We’ve got a lot of what it takes to get along

We’re in the money

The sky is sunny

Old man depression, you are through you done us wrong, oh

We never see a headline

‘Bout a breadline today

And when we see the landlord

We can look that guy right in the eye

Oh, We’re in the money

Come, on my honey

Let’s lend it, spend it, send it rolling around…

And lo it came to pass that Pfizer and I were no longer friends. But there was a time when I like to think we could have danced all night, and still have begged for more. I could have spread my wings, and done a thousand things, I’ve never done before. Yes, my bandwagon would have been much better. Better music too. John Martyn, Fleetwood Mac, Randy Newman, The Pretenders, Jools Holland ….

Yes, it’s a little bit funny that Pfizer knew, thirty years ago, that blood clotting and atherosclerosis were intimately connected. They had seen the research. They knew:

‘Important evidence is now emerging that the selective alpha-1 inhibitor, doxazosin, in addition to its beneficial effects on elevated blood pressure and the serum lipid profile, may help to intervene in the evolution of thrombosis, a key component of atherosclerosis.’

In my recent book The Clot Thickens, I said I would put up the Pfizer booklet for all to see. It proved a bit more of a technical challenge than I thought, but here it is. And when people tell me that atherosclerotic cardiovascular disease (ASCVD) is all due to raised cholesterol I can say, not even Pfizer believes that. Not really. Not deep in their hearts …. They have a ghost in the machine that still stalks the corridors of Pfizer HQ. And if it doesn’t, it should.

They knew, oh yes once upon a time, they knew. It’s just not very profitable for them to admit it. To quote John Martyn:

Half the lies I tell you are not true.’

Introduction

To date, most of our attempts to prevent atherosclerosis have centered on the control of hypertension and hyperlipidaemia, as well as lifestyle factors . However, recent insights into the pathology of coronary heart disease have sharpened our focus on the natural history of atheroma and its relentless progression to acute cardiac events.

Platelets and atherosclerosis progression

Several features of mature plaques, such as their multi-layered pattern, suggest that platelet aggregation and thrombus formation are key elements in the progression of atherosclerosis. Platelets are also known to provide a rich source of growth factors which can stimulate plaque development.

Given the insidious nature of atherosclerosis, it is vital to consider the role of platelets and thrombosis in this process, and the serious events that may be triggered once plaques are already present.

Fibrinolysis

If fibrinolysis is incomplete, thrombus may become incorporated into the plaque, and may cause severe stenosis. Alternatively, any residual thrombus can act as a powerful stimulant to further platelet aggregation. The growing mass of fibrin, platelets and enmeshed red cells may become solid enough to cause complete vessel obstruction.

It is significant to note that complete obstruction and myocardial infarction often develops from mild lesion initially causing less than 50% stenosis. Rupture of these plaques and the cascade of events that leads to thrombosis can occur rapidly and it now recognized as a common and major precipitant of unstable angina, myocardial infarction and sudden cardiac death. Studies suggest that thrombotic events may account for up to 90% of acute myocardial infarction.

Triggering factors in thrombosis

Hypertensive patients are known to have greater platelet adhesiveness and aggregability, which could increase clot formation at the site of plaque injury. In addition, thrombolysis is often defective in hypertension and hyperlipidaemia, which may result in an impaired ability to dissolved clots in the presence of atherosclerosis.

Clot propagation

Any residual thrombus can act as a powerful stimulant to further platelet aggregation. The growing mass of fibbing, platelets and enmeshed red-cells may become solid enough to cause complete vessel obstruction.

It is significant to not that complete obstruction and myocardial infarction often develops form mild lesions initially causing less than 50% stenosis. Rupture of these plaques and the cascade of events that leads to thrombosis can occur rapidly and it now recognized as a common and major precipitant of unstable angina, myocardial infarction and sudden cardiac deaths. Studies suggest that thrombotic events may account for up to 90% of acute myocardial infarctions.

The atherosclerotic process begins with infiltration of low-density lipoproteins or LDL into the arterial intima to create lipid-rich foam cells which form the basis of the ‘fatty streak.’ This early lesion contains large amounts of cholesterol, but its development to atherosclerosis is not inevitable. Progression appears to depend critically upon endothelial injury, caused by oxidation of LDL by the shearing forces of hypertension and by smoking.

Conclusion

With each decade, new insight is gained into how drug therapy can reduce the risk of coronary heart disease and stroke, the primary goal in the management of the hypertensive patient.
Important evidence is now emerging that the selective alpha-1 inhibitor, doxazosin, in addition to its beneficial effects on elevated blood pressure and the serum lipid profile, may help to intervene in the evolution of thrombosis, a key component of atherosclerosis.

The Document is called Pathological Triggers ‘New Insights into Cardiovascular Risk.’

Produced by Medi Cine Inc
488 Madison Avenue
New York
NY 10022

For Pfizer Inc
New York
NY 10017 Copyright 1992 Pfizer Inc. All rights reserved.

229 thoughts on “Pfizer and me – Best Buddies

        1. sabandy56

          Thank you for sharing what you have learned. My husband recently had a heart attack and a quadruple bypass. He has soft plaque and a family history of clots. I will ask his doctor about doxazosin. He wants him to take a statin which I disagree with one hundred percent.

          Reply
  1. aaronsinclair99

    Thank you.
    As an aside, you mention BP controlling drugs and aspirin. I am sure both are of great interest to your readership.
    I am currently considering giving up my statin but I’m still on med for hypertension.
    I’d like to be drug free… do anti hypertensives do what they say on the label?
    A deep dive into the pros and cons of taking small dose aspirin would also make an interesting read.
    Thanks again for the work you do.

    Reply
      1. Cathy Bell

        Or you can just eat whole foods, including plants. Gimmicks not needed to lower cholesterol. Eat low carb, high healthy fats, no processed foods, seed oils, or sugar, and your liver does the rest.

        Reply
        1. Eggs ‘n beer

          Worked for me. My GP calls it a bacon and eggs diet. Dropped my cholesterol by 20%. First time it’s ever been in the “safe” zone. She has another patient did the same with the same result.

          Reply
          1. Prudence Kitten

            I have just read Dr Shawn Baker’s “The Carnivore Diet” and I found it very convincing. He is an extremely good writer – up there with Dr Kendrick, whom he recommends – and says, among many other interesting things, that many people have found their blood pressure lower on an all-meat diet. It doesn’t have to be exclusively meat – a few above-ground plants are OK, such as leaves, broccoli, asparagus, tomatoes. But better to stick with all meat until down to a healthy weight.

          2. An Italian Australian at the tropics

            Carnivore works for me, and I use it from time to time when my old issues flare up, but it’s culinary boredom after a while.

            Adding a few selected vegetables helps a lot, some green peppercorns and finely sliced raw Russian (geez, is still allowed?) garlic in a butter and cream sauce makes any steak much better, a little homemade kimchi and sauerkraut with a crispy shoulder pork chop is heaven, a drizzle of extra virgin olive oil on a grilled red emperor fillet is much better than butter, and so on.

            Then of course there is coffee, wine and cognac.

            As for vitamin C, even if you cannot get scurvy on a carnivore diet, I prefer to supplement it to compensate for our immense EMRs exposure, something that our ancestors certainly never experienced. Unless you live in the bush without electricity and away from any broadband tower, if such a place even exist anymore, you’d need a lot of vitamin C to keep your REDOX just right.

          3. Eggs ‘n beer

            I know! First time I’ve been worried about my cholesterol ….

            Prudence, indeed, BP 113/76 at 63 years.

      2. Fran Leigh

        You missed the whole point of this blog. Lowering cholesterol with either statins, non-statins or supplements designed to lower cholesterol, will not prevent a heart attack or stroke.

        Reply
        1. Janet H

          Indeed. I ignore my cholesterol. Im a 73 yo woman and I prefer higher cholesterol. I eat clean and keto/carnivore.

          Reply
      3. DV

        sounds good in theory but didn’t work for me — took a plant sterol for two years and no lowering of cholesterol.

        Reply
      4. Sue Madden

        why would anyone need to combat high “cholesterol”? My total cholesterol is around 325 mg/dL (not sure of the units sorry) and I`ve been trying to find a way of getting a Tshirt made with “I love my (high) cholesterol”. I`ve of course read everything Malcolm has written (including the latest block-buster – fantastic). Mine was always 250 or so and I never worried about it (never found the whole crazy story convincing) – so have been thrilled to find out the true story over the last few years only, Thanks Malcolm, you have many fans out there!! When you get round to thyroid I`d love to tell you my investigative story – another can of worms …

        Reply
        1. AhNotepad

          I have no idea what my cholesterol is. My system is probably taking care of it, so why would I trust someone who gets an incentive from the manufacturer of a pill to do it better?

          Reply
          1. Prudence Kitten

            As habitues of social media often say, “This!”

            AhNotepad has struck the nail smartly on the head, driving it deep into the underlying wood.

          2. sticky

            Magnesium is a natural statin, according to Carolyn Dean MD in The Magnesium Miracle.

            She explains that magnesium expert Dr Mildred Seelig co-wrote a paper showing that magnesium acts by the same mechanisms as statin drugs.

            The production of cholesterol requires a specific enzyme called HMG-CoA reductase. It turns out that magnesium slows down this enzymatic reaction when cholesterol is present in sufficient amounts, and increases it when more is needed. HMG-CoA reductase is the same enzyme that statins target and inhibit.

          3. sticky

            Dean goes on to say:
            “If sufficient magnesium is present in the body, cholesterol will be limited to its necessary functions – the production of hormones and the maintenance of membranes – and will not be produced in excess. Remember, most of the cholesterol in the body is produced in the liver, so if it’s not needed, the body won’t produce it – but this mechanism depends on having sufficient magnesium.
            “It’s only in our present-day circumstances of magnesium-deficient soil, little magnesium in processed foods, and excessive intake of calcium and calcium-rich foods, without supplementation of magnesium, that cholesterol has become elevated in the population. If there is not enough magnesium to limit the activity of the cholesterol-converting enzyme, we are bound to make more cholesterol than is needed.
            “The magnesium/cholesterol story gets even better. Magnesium is responsible for several other lipid-altering functions that are not even shared by statin drugs. Magnesium is necessary for the activity of an enzyme that lowers LDL, the ‘bad’ cholesterol; it also lowers triglycerides and raises the ‘good’ cholesterol, HDL. Another magnesium-dependent enzyme converts omega-3 and omega-6 essential fatty acids into prostaglandins, which are necessary for heart and overall health. Seelig and Rosanoff conclude their paper by saying that it is well accepted that magnesium is a natural calcium channel blocker, and now we know it also acts like a natural statin.”

        2. Harry de Boer

          Right. We already know that Ancel Keys’ study into cholesterol as cause of CVD was fraudulent and that John Yudkin with his ‘Sugar, the white poison’, was right.
          Cholesterol is not the problem, the excess of (fast) carbohydrates is (an important contributor).

          Reply
      5. jeresavo1

        I care not about my cholesterol levels. Its not a thing, its only ever an issue because of manufactured unrealistic anxiety promoted by the market people on behalf of the money men. From “The Clot Thickens” it appears that the only time cholesterol becomes a factor, maybe a necessary factor, is when Vit C levels are low and the lpa is rushed in to do a quick repair job to prevent excess bleeding.

        Reply
    1. andyS

      Decided today to go off blood pressure medications, Carvedilol (beta blocker) and perindopril (ACE inhibitor). Main reason is adverse effects. These medications appear to correct problems caused by high glucose, high insulin, high fructose, and linoleic acid (PUFAs). First step is to eliminate these items from your diet, then monitor blood pressure before stopping medications. Based on information gathered from internet.

      Reply
      1. mmec7

        Had to smile, andyS – as couldn’t agree more. I tried the BP meds lark. High BP with alarming ‘spikes’. Well, 16 BP meds later, with horrible and continuing reactions, I gave the lot a kick out of the door. Now and again I use L’Arginine Ketoglutamate. No problems. Fortunately, I dislike sugar, cake, biscuits and detest chocolate. Fructose, only in the fresh fruit I eat from time-to-time – no fruit juices, horrible. No PUFAS – the only fats that come into my house are, BIO butter, BIO Coconut Oil, and the occasional use of BIO cold pressed Olive Oil. (detest salad dressing.) Fortunately, I also dislike fried foods, and the smell of cooking oil is sickening. The nearest I get to anything ‘fried’ is the occasional egg, and then, in coconut oil, (one only needs a desert-spoon of c’nut oil) : black pepper with a shake of curcumin, then dusted with Provencal herbs. Pretty yummy. I don’t eat crap food, and studiously read labels. NO dried meats and very little red meat – dislike beef. Good cookware – like iron and stainless steel. No aluminium.
        Right, said Fred, that’s enough o’that.

        Reply
        1. Junkgirl

          I live about like you for years and my BP is still high. I walk miles and strength train. I’m 73 yo woman. My stress level is very low right now and still get high readings. (135-160) I had a stress test and it looked ok. I do hate putting that cuff on and can feel a change in my heartbeat and become a little anxious. I’m on a low Losartan dose but would love to get off this. How? I wonder if some of this is just fear of the cuff now. I had a scary doctor before surgery in 2019 who frankly frightened me so much I’ve been scared of taking BP ever since. I was in her office right after an accident facing surgery the next day and she was all over me about my BP. I won’t go back to her now. I see a functional medicine doc but she has kept me on the med while my high lead and arsenic levels are coming down and while working on my Hashimotos outside of the usual Rx Synthroid. I feel fabulous.

          Reply
          1. sticky

            You could buy a home BP monitor, so that you can check it yourself, without being stressed out by a white coat. They are quite cheap, and my Omron one seems to be fairly accurate.

    2. Gary Ogden

      aaronsinclair99: Back in one of Dr. Kendrick’s Roman numeral heart disease posts there was a long commenter discussion of BP drugs. I gave great consideration to the known facts, and decided to go drug free (never took a stain). I think it was four years ago. One of my major considerations was that increasing potassium intake is very good for our health, and ACE inhibitors are potassium-sparing, so supplementing is not a good idea. I was on as many as three at one time, including a beta blocker, a diuretic, and an ACE inhibitor. I weaned off each one, in that order. One of the most convincing arguments is that BP guidelines are much too conservative, particularly as we age.

      Reply
        1. Eggs ‘n bacon

          That seems to be another benefit of my ‘bacon and eggs’ diet, as my GP refers to it as. BP 113/76, at age 63. I am not a fitness freak either, a 5km walk most days is my limit. Gyms are anathema.

          Reply
        2. Gary Ogden

          Mr Chris: That’s right. It is normal for BP to rise with age as the body seeks to perfuse the organs with sufficient blood for optimal functioning in a system getting a bit creaky from the normal aging process.

          Reply
          1. andyS

            If you are worried about blood pressure, adrenaline from the chronic stress will raise your blood pressure. A beta blocker will help to reduce blood pressure and please the cardiologist.
            Confounding factors, chronic hyperinsulinemia/hyperglycemia, sympathetic nervous system activation, and linoleic acid. Orange juice consumption?

  2. Carole

    30 years of making money rather than being the company that really helped mankind with atherosclerosis and made money into the bargain!
    I suppose they still have that drug in their back pocket as opinion swings away from cholesterol?

    Reply
    1. oliveira

      Do you think that Chemie-Grunenthal did’nt continue studying Thalidomide biochemistry? On those times many genial minds were paid for good ideas.
      Treatment for Leprosy and Myeloma ensued.

      Reply
    2. Prudence Kitten

      “No man can serve two masters: for either he will hate the one, and love the other; or else he will hold to the one, and despise the other. Ye cannot serve God and mammon”.
      – Matthew 6:24

      No doctor, scientist, or corporation can serve two masters: Ye cannot serve healing and mammon.

      That’s almost the whole problem.

      Reply
  3. Peter Swettenham

    Frm NHS web site – not sure I want to try doxazosin!

    Side effects of doxazosin
    Like all medicines, doxazosin can cause side effects, but many people have no side effects, or only minor ones.

    Side effects often improve as your body gets used to the medicine.

    Common side effects
    These common side effects of doxazosin happen in more than 1 in 100 people. They’re usually mild and only last a short time. There are things you can do to help cope with them:

    Feeling weak, sleepy or dizzy
    Headaches
    Swollen feet, ankles or fingers
    Urinary tract infection (UTI) or cystitis
    Stomach pain or back pain
    Feeling sick (nausea), indigestion or heartburn

    Talk to your doctor or pharmacist if this advice does not help or the side effects last more than a few days:

    Serious side effects
    Tell your doctor or contact 111 straight away if:

    the whites of your eyes turn yellow, or your skin turns yellow although this can be harder to see on brown and black skin – these can be signs of liver problems
    you get unexplained bruising or bleed easily – these can be signs of a blood problem

    Reply
  4. abamji

    Can’t make a rhyme?

    The total or partial ablation
    Of tiresome platelet aggregation
    Means you can relax,
    For arterial plaques
    Will be notable by their cessation.

    Must try harder, Kendrick!

    Reply
        1. Tish

          And what about “You’re not funny and nobody’s laughing” followed by the blackboard rubber hurtling towards you. Happy days!

          Reply
          1. Ruth Baills

            I remember 😃😃😃 those days. Duster flying to me and one day it flew right out the window. I was made to go and retrieve it LOL

          2. Prudence Kitten

            Mr Sale (confined to a wheelchair by polio) had remarkably strong arms and superb coordination. With no detectable backswing or warning, he routinely pinged a supersonic piece of chalk off the wall about 2 inches from one’s ear – and never hit anyone. It kept you on the mark.

            Mr Weeks, by far the shortest and thinnest teacher, scorned such means. His glance seemed as if could freeze a charging gorilla in its stride. The only warning he ever used was to speak a little more quietly. No boy ever found out what the next step was.

          3. Marty G

            Yes, crappy days. Back in the 1970’s most of my teachers were sadistic bastards. When I mentioned the board rubber thing at home my dad said that if he could be bothered to get up, HE’D give me a whack for being such a mardarse So I learned to grin and bear it.
            When I was eleven all the grammar schools in my town became comprehensives. I wonder If that perceived demotion made the teachers lash out at us kids?

  5. Bill Sanderson

    Lovely long word ‘pleiotropics’ which I hope to drop into many conversations from now on. A few years back my increasingly frequent visits to the toilet led me to being diagnosed with prostate cancer. In the interval before treatment my doctor prescribed doxazosin to ease my bladder problem -Voila! It worked. It was several months later when I realised that I no longer had a prostate to speak of (no pressure on urethra) that I stopped the prescription…

    Reply
    1. Prudence Kitten

      So might the trick have been to take it for a fraction of the time? (Although obviously you would follow the doctor’s instructions).

      Reply
    2. Harry de Boer

      Do you mean it reverses hyperplasia?
      Now I’m interested.
      How long did you taken it and in what dose?

      Reply
    1. Cathy Bell

      Oh dear, 80mg of atorvastatin. That is bad. Some drs. think prescribing a megadose of a statin for it’s supposed anti-inflammatory benefits is a good idea. Terrible, terrible idea. The last thing people who are having heart or stroke problems needs is to lower their cholesterol, especially with 80mg! (or any dose, for that matter) How do some drs. think this is a good idea? In my reading travels over the last 5 years, I’ve yet to come across a RCT proving statins have some s9rt of worth as an anti-inflammatory. I see lots of patients now with diabetes, muscle damage, neuropathy, and know a couple of people who have died from ALS-type statin injuries. I am going to send a note to FLCCC.

      Reply
      1. Prudence Kitten

        Very interesting and convincing talk about why lowering inflammation is often a bad idea too.

        “Fever, Fluids, Food in acute infections”

        Dr Stephen A Hoption speaking; hosted (only) by Dr John Campbell.

        Reply
      2. MarciaT

        Cathy Bell – At least you know the people at FLCCC will listen – unlike too many in the medical profession these days.
        Thanks again, Dr. Kendrick, for a brilliant column – what would we do without you???
        And speaking of drug companies, If anyone knows which company foisted the flouroquinolones on society, (it was the anthrax scare, remember?) could they let us know? FDA approved (naturally) but they now have a black box warning because of the disastrous side effects. Sigh.

        Reply
  6. Ruth Baills

    Thank you Dr Malcolm Kendrick again for your blog. Much at. I am currently reading your book “The Clot Thickens”. Amongst the serious stuff I get to laugh out loud at your sense of humour.

    Reply
  7. David Carter

    I have followed your blog for 10 years plus and I have to say that was the best, most informative and amusing piece I have ever read. Congratulations!

    Reply
  8. Robert Dyson

    “The atherosclerotic process begins with the infiltration of low-density lipoproteins or LDL into the arterial intima ….” Oops!

    Reply
    1. Robert Dyson

      Yes. I read all of Malcolm’s posts. They are informative, clearly written, with that touch of humour to give the mood a lift. He is providing health care to many just with that humour. A truly good person.

      Reply
  9. vermontresident

    Thank you, Malcolm, fascinating! However, my first thought regarding Pfizer is, “Were you lying now, or were you lying then?” My trust level of all Pharma is now in the negative. “It’s Safe and Effective!” now makes me ask, “Safe and Effective for whom?” It seems that with any drug these days, it’s “safe” if it’s hard to pin the negative side effects on the company, and it’s “effective” at generating enough profits to offset any lawsuits for wrongful death!

    In other news, to try to protect my arteries from stress hormones, I have been trying to relax more by occasionally having a tiny glass of Chartreuse after dinner. The monks have been making it for hundreds of years, and apparently only three monks now the recipe. It is now my placebo of choice!

    Reply
    1. Prudence Kitten

      ‘However, my first thought regarding Pfizer is, “Were you lying now, or were you lying then?”’

      Or both? (With grateful thanks to Dudley Moore in “Beyond the Fringe”).

      Reply
    2. Shirley Nicholson

      Chartreuse, the yellow or the green? I used to quite like the yellow, whereas the green was only fit for cough mixture!

      Reply
  10. vermontresident

    Have you considered posting on Substack? You could easily solicit both free and paid subscribers — I’d be pleased to pay for your excellent content!

    Reply
  11. Robert Dyson

    “False-color angiogram of coronary artery stenosis”. Is there a hidden message in this – the confusion of mental stenosis? That ‘false’ is another clue. Must have been a very insightful medical copywriter.

    Reply
  12. John Mayes

    “The growing mass of fibbing, platelets and enmeshed red-cells …” should be:
    “The growing mass of fibrin, platelets and enmeshed red-cells”. I think the fibbing came later.
    Also in the next paragraph “not” should be “note” ie It is important to note.

    Reply
    1. SteveR

      “The growing mass of fibbing” – brilliant Malcolm! I think you’ve stumbled on the title of the follow-up to “The Clot Thickens”

      Reply
  13. Sandi Davenport

    Both of parents’ death certificates listed “atherosclerotic heart disease” as their causes of death. The minute my doctor heard that he prescribed Lovastatin for me. Ten plus years later I questioned it. My new doctor told me that I shouldn’t stop taking the statin until I had some kind of heart test done (not covered by Medicare). I continue to get the 40mg daily prescription filled but don’t take them? Your articles make sense to me but now I wonder should I be taking y’a small dose of aspirin daily.

    Reply
  14. Pauline Sandrin

    Can you stop taking statins after 3 to 6 months & does it create problems?? Thanks for your reply

    Sent from my iPhone

    >

    Reply
  15. Robert Dyson

    Delayed thought. Capitalism runs for sharholder value (or owners and top execs) but it has nothing against selling something that works. Just as a stopped clock is right twice a day, sometimes the pharma industry produces something good. It was better before ~1980 when the greed is good really took off. It needs strict regulation but over time has captured those agencies meant to reglate it.

    Reply
  16. Debbie

    I got a chuckle out of your comment on statins not being used for covid. I believe one of the statins is being used for covid. And a recent preprint for long Covid showed success with pravastatin along with maraviroc: https://www.researchsquare.com/article/rs-1344323/v1

    Interestingly, one of the ‘off target’ or pleitropic effects of some statins is to promote the formation of pro-resolving lipid mediators, which may hold the key to the resolution of atherosclerosis. Here’s some (older) review article on it: https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC3027152/
    And my recent article: https://www.geneticlifehacks.com/specialized-pro-resolving-mediators-getting-rid-of-chronic-inflammation/

    Reply
    1. thecovidpilot

      Isn’t it funny that vitamin D regulates inflammation-reduction in the body? Could adequate levels of nutrients be the key to a lot of our fast-food-world problems?

      Reply
      1. Prudence Kitten

        There is sufficient evidence that people eating only meat do not get scurvy (ever). Maybe Vitamin C is an antidote to processed grains and sugar.

        Reply
          1. Prudence Kitten

            I dropped all fruit juices, etc. a while back – too much sugar. Nowadays I see all refined carbs and vegetable oils as the enemy – but above all I strive to keep my blood sugar as low as possible.

          2. AhNotepad

            I would say orange juice is not much good for vitamin c. Too much sugar, so it negates the effect of the vitamin C to some extent.

          3. thecovidpilot

            Things keep getting more complicated.

            “Effects of Citrus Fruit Juices and Their Bioactive Components on Inflammation and Immunity: A Narrative Review”

            “Important bioactive polyphenols in citrus fruit juices include hesperidin, narirutin and naringin. Hesperidin is a glycoside of hesperetin while narirutin and naringin are glycosides of naringenin. Hesperidin, hesperetin, naringenin, naringin and narirutin have all been found to have anti-inflammatory effects in model systems, and human trials of hesperidin report reductions in inflammatory markers. In humans, orange juice was shown to limit the post-prandial inflammation induced by a high fat-high carbohydrate meal. Consuming orange juice daily for a period of weeks has been reported to reduce markers of inflammation, including C-reactive protein, as confirmed through a recent meta-analysis.”

            https://www.frontiersin.org/articles/10.3389/fimmu.2021.712608/full

          4. An Italian Australian at the tropics

            Living at the tropics and loving the sun, it’s best to keep citrus consumption (and celery) to a minimum, is significantly increases the risk of melanoma.

            And I like too much the ketogenic version of me anyway.

          5. thecovidpilot

            I saw a 2015 article about citrus and melanoma. Perhaps people in the tropics avoid the sun generally and are deficient in vitamin D which might increase their risk of melanoma? Incidence of vitamin D deficiency in India runs

            “The prevalence of Vitamin D deficiency ranged from 40% to 99%, with most of the studies reporting a prevalence of 80%–90%. It was prevalent in all the age groups and high-risk groups alike.”

            https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060930/

          6. An Italian Australian at the tropics

            I believe that sunlight, as pretty much everything else in nature, is a double edge sword.

            Go sunbathing at the tropics for 6 hours when you are of Irish heritage and you haven’t exposed your skin to the sun for month can’t be too healthy. Spend half an hour a day and slowly increase your exposure, better early in the morning or late in the afternoon (UVs here are strong even at those hours) on the other hand…

            But anecdotally I’ve only seen melanomas in people who never sunbathed, ate a diet full of carbohydrates and seed oil and had a generally unhealthy (but healthy for the GPs) lifestyle.

            I go to the beach for a few hours or more every day, including at midday, I never burn (even if my mother was a ginger) while before, on a SAD diet, I couldn’t even tolerate the sun of the Northern Mediterranean sea without badly burning my skin and getting a terrible erythema.

            The problem with citrus is their furocoumarins content, even a serve a day of orange juice seems to significantly increase melanoma risk, and some lime varieties, very popular around here, are the worst.

          7. thecovidpilot

            Half an hour of exposure for someone with light skin could result in a minor burn. It’s more of a problem at high altitudes because UV intensity is higher at high altitudes. Otoh, vitamin D production is also higher, so less exposure time is required to get the same vitamin D production as at lower altitudes.

            Melanoma is low risk for people with fair skins because it’s caught early, generally.

  17. Binra (@onemindinmany)

    The pathology is in the adopted and invested model.
    Hence the blind watchmaker ‘finds’ mechanisms to provide gain of function to the protection racket that retains the term ‘cure’ for attracting investment and sales PR as code for future profits, and the proverbial carrot on a stick.
    A materialistic model for life, biology or health is at best a systemic conflict/risk reduction modelling to which life is then sacrificed under the high priests of The Science.
    The same could be said of geopolitics in reference to risk of loss of profits, assets and possession of those whose economic models embody an entropic conflict set in scarcity – and generate such, just as allopathic pharma generates sickness, disease and death.
    The psycho physical nature of biology is being revealed by the intent to hack the biofield.
    When the great gene promise failed its global stakeholders, they doubled down in it biomarker basis for new narratives to exploit, while covering for the failure to actually find viruses in sick people. While incorporating the other side of biotech – of biofield hacking. I may add that the spontaneous organisation of the electromagnetic structuring and function of blood in vivo underlies all chemical interactions right down to nanoscale particles and nano-current signalling. It is also in ‘concert’ with cosmic weather or solar fluctuations to the exogenous terrain to our planet’s ‘cellular membrane’ which is principally an electromagnetic phenomena.
    In time, we will shift from a force based model of life to a resonance based model for life. Perhaps now, perhaps one now at a time, perhaps as a result of releasing the attempt to force perceived symptoms of dysfunction, into fitting a pathological model.
    Iatrogenic disease is not a side effect, but a direct consequence of abnegated responsibility in both physician and patient. – much of which is a culturally conditioned ‘freedom’ to persist in self-illusion while masking over evidences that – if addressed honestly – would invalidate the model and treatment protocols.

    Reply
    1. Dr Zhivago

      TWIMC:
      Binder snapped copper flood is like proximal hyperplasia to floppy discs – cryptic data and biometric flabbergasted; lost the audience, gibberish.

      Reply
  18. Rob Hanna

    Great post: my take away is simple aspirin (acetylsalicylic acid) is now the “apple a day to keep the ER away” for cardiovascular health. Good principle for everyone?

    Reply
    1. Eggs ‘n beer

      No. If you’re prone to haemorrhages it’ll kill you with a stroke. After six weeks of 100mg once a day (after vaccine induced mini-strokes) the m-i-l’s legs started bleeding. Stopped the aspirin and the bleeding stopped within two days. She’s 91 next month, and that’s the only medication she’s ever had. (Vaccines don’t count as medication).

      My Dad died of a haemorrhagic stroke (many years ago, pre covid) after being prescribed blood thinners, they assumed he’d had a mini-stroke caused by clots, whereas he’d just had a fall. Previously had a haemorrhagic stroke.

      Reply
    2. thecovidpilot

      Aspirin may work for clots that rely on fibrin and platelets, but at least some covid clotting seems to be caused by autoimmune disease. For the second type, antihistamines may help prevent autoimmune clots.

      Reply
  19. tonykerstein

    I was on low dose aspirin and I got a brief haemorrhagic stroke. It was immediately over leaving a small blood clot on the brain. Your book the great Cholesterol Con got me off statins, another anti coagulant, which may have saved my life. The point is that low dose aspirin also has its risk

    Sent from my iPhone

    Reply
  20. Cynthia Anderson

    Dr. Kendrick,

    I just read this and have saved the download to a file in my documents. Thank you. This makes so much sense. I am going to share it with my cardiologist as along with aortic stenosis I also have some narrowing of the arteries. Good information!

    Reply
    1. Prudence Kitten

      The Oxford English Dictionary says it should rhyme either with “black” or with “dark”. It’s from Dutch, apparently.

      Reply
      1. Martin Back

        The Concise Oxford agrees. -k or -ark.
        Apparently from the French ‘plaque’ pronounced “pluck-oo-ay”(?), originally from the Dutch ‘placken’.
        In Afrikaans ‘plak’ pronounced “pluck” means patch or affix. Die gat in die muur was geplak met ‘n plakkaat vasgeplak met plakstof. “The hole in the wall was patched with a poster fastened with adhesive.”

        Reply
  21. Jef Jelten

    All these folks are doing nothing wrong. Pharma or any other industry in the capitalist system for that matter, they are all playing by the rules and whether or not you like it they are winning.

    Don’t hate on the players, hate the game!

    Reply
    1. AhNotepad

      They are doing nothing wrong”.

      So why do the likes of Merck, Pfizer, GSK, etc get such large fines for their misdoings?

      Reply
      1. Jef Jelten

        Believe it or not those are all part of the rules. They budget for those outcomes. Does anybody or anything stop them? NO! Because thats called winning in this game.

        Reply
        1. thecovidpilot

          Your response to AN is irrelevant to my comment. There was a time when justice and fraud were punished. Pfizer has been fined billions of dollars and so was Glaxo SK. Their stock plummeted. That wasn’t “winning.”

          Problems with capitalism can occur when there is too little competition and when capital gets aggregated in a few very large hands.

          Capitalism can be run on a win-win proposition rather than on a “I win-you lose proposition.” Adam Smith wasn’t wrong. The problem occurred when mergers allowed capital to be combined into a few large hands. I favor progressive tax rates on corporations up to 90% at the top and a disallowance of _all_ legislated deductions _for corporations_. Deductions always favor the wealthy because they know how to take advantage of them.

          We see lots of benefit from capitalism practiced by small and medium size companies.

          Not so much by the Fortune 500.

          There is also a huge problem with training in business schools as regards ethics.

          Now you see problems with ESG being applied to huge companies and the “woke” global elite through Vanguard and Blackrock leveraging ESG to increase their power and take our freedoms.

          Again, without the huge accumulation of capital, none of this could happen.

          Reply
        2. AhNotepad

          So it’s all a game to you? Effin serious if you get serious damage or killed. Why do I get the impression you condone harming people?

          Reply
  22. thecovidpilot

    It seems that most people on “the other side” believe what they do because public health authorities have told them what to believe and most people trust public health authorities. So, it seems that in order to eliminate this blind trust, the reputation of PHAs must be undermined. And it seems that the way to undermine the trust is to show that PHA’s “mistakes” have been in a consistent direction–for the benefit of covid vaccines. So I put together a post about this on my site whose purpose is to undermine the reputation of public health authorities.

    Reply
    1. Prudence Kitten

      “So, it seems that in order to eliminate this blind trust, the reputation of PHAs must be undermined”.

      Hard to imagine anyone else could as good a job of that as they have been doing themselves.

      Reply
  23. nestorseven

    Another good article. I am taking 180,000 KHU cayenne tincture, nattokinase and hawthorn berry and a few other things. No drugs or even baby aspirin. My doc wants me on statins and others and do a stent. Not buying it.

    I view the drug industry as highly criminal in many respects. Even more so after reading Mad In America, a well written book about the history of mental health care over the last 100 years. It’s more terrifying than any horror movie I have seen.

    I believe medicine (medical care) should be designed to keep you off of drugs…and not tell you from the get go that you will have to take this drug or that drug for eternity. Prove to me that most of these concoctions make you healthier or extend your life.

    Reply
  24. The Underdoug

    “To be frank you would buy a used car from Pfizer. I don’t know how they got so brilliant at spraying bull-shit with yellow paint, to make it look like one-hundred per-cent gold bullion, but there is no doubt they are the masters of pharmaceutical marketing.”

    If the rubbishing of the Astra-Zeneca Oxford jab is anything to go by, I suspect that Pfizer’s marketing department has been earning their keep over the past 18 months (albeit under the radar). It seems that statin marketing (how many lives saved versus lives lost per x doses taken – although everyone seems to ignore the lives lost bit) is the template for one of the persuasion techniques used to induce the plebs to take ‘da jab’.

    Reply
  25. David Bailey

    “Last time I bothered counting, statins had thirty-four off-target effects”

    That left me very curious – are these effects predictable, based on the enzyme system (or whatever) they interact with, or just random?

    Has anyone tried to produce a map of all these off-target effects? Are they generally large enough to be usable?

    Could we shut down Big Pharma and just use the generic drugs that we have already?

    Reply
  26. Jerry White

    I sent your letter to my PC nephrologist and got this back “When tested in a large (41,000 pts with HTN) against other Anti-HTN drugs (ACEI, Thiazide type diuretics, Amlodipine) doxazosin was discontinued early because of a higher incidence of heart failure. The incidence of MI was no different between doxazosin and the others. (See ALLHAT Trial. )”
    I have two heart blockages I wanted to take what you suggested.

    Reply
  27. Gretchen

    “platelet aggregation and atherosclerotic plaques …. You certainly cannot get a rhyme out of that – go on, I challenge you.”

    Platelet packs and atherosclerotic plaques.

    Reply
  28. senorfrog123gmailcom

    Any thoughts on this on nether regions? Specifically Peyronie’s disease. Talked to urologist a couple times about a year apart, he said that it could even go away on its own. It actually more than doubled in size. Not especially painful and still functional but it is a bother emotionally and the physical ramifications.
    Thanks for any input you may have.

    Reply
  29. Robin Pierce-Williams

    Dear Dr Kendrick
    Really looking forward to your presentation at the conference on Saturday.
    There is an article in the Times this week championing the benefits of statins ( pretty much for all), with some additional claims for positive effects on Parkinson’s, prostate cancer and probably just about every other condition.
    If you have time on Saturday perhaps you would be willing to comment.
    Kind regards
    Robin.

    Robin Pierce-Williams
    07807950841

    Reply
  30. thecovidpilot

    I just posted about a cerebral venous thrombosis journal article on my site and look what popped up in my feed.

    https://www.msn.com/en-us/health/medical/risk-of-brain-blood-clots-significantly-higher-after-covid-infection-than-pfizer-moderna-shots-study-finds/ar-AAVeQsX?ocid=msedgdhp&pc=U531

    The shoddy Forbes article doesn’t even contain a link to the JAMA Network Open article. I found the article at

    https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2790206

    The journal article contained this joke that should be especially absurd to those in the UK: “In addition, because mRNA-based SARS-CoV-2 vaccination has been shown to prevent SARS-CoV-2 infection”.

    When you look at the article data, there is no concurrence of vaccination and covid, which is not believable. There is no statement of exclusion of covid diagnosis from the vaccinated cohort, either. This is another paper from the Journal of the American Misinformation Association that needs retraction or correction.

    Reply
  31. Justin Terested

    Dr. Kendrick: The moment I read your mention in “Clot” regarding the Pfizer booklet about “thrombosis, a key component of atherosclerosis” I was interested to see that publication, so I could read their “disappeared” narrative. Thank you for posting that PDF. But even more so, thank you for this terrific accompanying post that puts it all into complete perspective.

    Reply
  32. Eric

    Not about Pfizer and statins, but interesting, and I thought it would get lost if posted in the no longer that active experts thread:

    While there were considerable Covid deaths in Sourth Africa and yet more excess mortality that rose during the waves, and the same pattern emerged in India that is roughly similar in terms of median age and temperatures, While the experts cited do not fully agree, it appears not to have happened in countries closer to the equator such as Kenia or Serria Leone. Much is said about a weaker health system and poorer record keeping, while local experts say that funerals are very much noticable because they area big deal and the population is very much attuned to unexplained death waves because they have experience with Ebola and the like.

    Clearly, South Africa gets less sun exposure due to its latitude. On the other hand, while India is in the Northern hemisphere, at least its Southern tip is a lot closer to the equator than Northern South Africa is. So what else? Maybe a higher degree of industrialization results in higher prevalence of industrial foods in both countries but not so much in other sub-Saharan African countries? Could the comparatively strong health system be part of the problem?

    Reply
    1. thecovidpilot

      Access to tropical sun theoretically would allow more vitamin D production, but doesn’t practically, primarily for cultural reasons.

      Southern states in the US have a respiratory illness wave in summer, which may be because people avoid high temperatures and sun exposure in the summer. You might see the same thing in southern Italy, Spain, and Greece, but possibly the sea moderates temperatures in the summer.

      Reply
  33. Eric

    After sifting through the comment section of the NYT article, a few things come up repeatedly:
    – much of the population takes HCQ or other malaria drugs
    – much younger population even than in SA or India
    – less obesety
    – and one very interesting comment (though I wouldn’t agree that hypothiocyanite is a relative of chlorine bleach):

    Jonathan D. Kaunitz, M.D.
    UCLA School of Medicine
    March 24
    Populations in Western and Central Africa include cassava as a major source of calories. The African variant has a high content of the cyanogenic glycoside linamarin, which is converted to deadly hydrogen cyanide (HCN), requiring extensive preparation. HCN is detoxified to thiocyanate (SCN). Many of the West Africans populations suffer from forms of cyanide poisoning termed konzo. SCN is converted in the airway and salivary glands to the antiviral disinfectant OSCN (hypothiocyanite), a relative of household bleach (hypochlorite or OCl). We have hypothesized that ingestion of high amounts of cyanogens increases the concentrations of OSCN in the saliva and bronchial secretions, reducing the burden of virus, decreasing the infection rate: (Ingestion of Cyanogens from Cassava Generates Disinfectant Hypothiocyanite That May Decrease the Transmissibility of SARS-CoV-2 2021, Academia Letters DOI: 10.20935/AL1211). Further support of this hypothesis is in smokers, who are exposed to HCN in tobacco smoke and have high SCN levels. Although smokers with chronic lung disease have more severe COVID disease, smokers in general are less likely to become infected with COVID. There is indeed an inverse correlation between cassava ingestion and COVID death rate, explaining the low death rates in African cassava-consuming countries, especially Nigeria and the DRC.

    Reply
    1. thecovidpilot

      “OSCN (hypothiocyanite), a relative of household bleach (hypochlorite or OCl)”

      (A minor, geeky chemistry point) This is incorrect. The active agent of household bleach is chlorine, which exists in an oxidized state in bleach and is a strong oxidant itself.

      Reply
    2. An Italian Australian at the tropics

      “Although smokers with chronic lung disease have more severe COVID disease, smokers in general are less likely to become infected with COVID”

      Says a test not designed to diagnose infections, about a disease whose diagnosis is possible only through such test (catch 22 anyone?).

      Reply
  34. Kristina Alexander

    RE: Doxazocin: Hello Dr Kendrick, I love your humour despite the serious content. I wish all doctors had your intelligence and open-mindedness to be able to think for themselves and not allow themselves to be brainwashed. We have too much of that as it is. I wish I lived in Scotland and had you for my GP. The GP’s at the practice where I love (Harrow) are lovely, bless them, but seem unable to think holistically. That believe is a problem within the NHS and its old-fashioned ruling Body. I am 76 and am taking 20mg each of Amlodipine and Lisinopril. They create nausea and dizziness and just make me feel unwell. At times I just want to “go to Switzerland” if you know what I mean. Anyway, can I ask my GP to put me on Doxazosin? If not, can I fight the NHS for it? By the way, being the open-minded man you are, Dr Royal Rife in the 1920s discovered Frequencies could heal just about everything (Einstein-Everything is energy). I am using free Rife frequencies on youTube to try to help myself. Also there is now Quantum energy healing (contact Dr John Ryan who works in an Ottawa hospital and also channels quantum healing from the light beings on Syrius). Lovely guided healing meditations. Quantum healing technologies are becoming available now if you can afford them. The medical system in the UK is so outmoded it’s not even funny. They don’t even recognise Homeopathy-which is an energy frequency based system using Mother Nature. I could go on forever. Bless you for your common sense and fearless revelations.

    Reply
    1. Henry Smith

      Keep taking the meds Kristina.
      “In a churchyard by a river, lazing in the haze of midday
      Laughing in the grasses and the graze
      Yellow bird, you are not alone in singing and in flying on
      Laughing and in leaving
      Willow weeping in the water, waving to the river daughters
      Swaying in the ripples and the reeds
      On a trip to cirrus minor, saw a crater in the sun
      A thousand miles of moonlight later”
      Cirrus Minor, Pink Floyd.
      [https://www.youtube.com/watch?v=GfPVM5dFlp8]

      Reply
  35. andyS

    HISTORICAL CVD CAUSES
    1 Saturated fat: PROVEN FALSE
    2 Cholesterol: STILL IN VOGUE
    3 Blood pressure: CURRENTLY CONSIDERED MAIN CAUSE
    4 Platelet activation: ANTI COAGULANT TREATMENT PART OF PROTOCOL

    Cardiologists will prescribe medications for #2, #3 and #4.
    Blood pressure and its treatment apparently not the solution. As a root cause would add;
    5 Chronic Inflammation: caused by insulin resistance, hyperglycemia, hyperinsulinemia, fructose, linoleic acid (pufa), mitochondrial dysfunction etc..
    A patient might do better to switch from pharmaceuticals to nutraceuticals.

    Reply
  36. Jeremy May

    The integrity of Pfizer et al. is called into question (to put it politely) by Dr John Campbell.

    The video is based on a peer reviewed article in the BMJ titled, ‘The Illusion of evidence Based Medicine’ in which the authors claim, “Evidence based medicine has been corrupted by corporate interests, failed regulation, and commercialisation of academia.”

    Not a new concept to some of us, but another widely-watched condemnation of where we are.
    (In fact views have doubled to 184,000 in the past 3 hours).


    One to forward perhaps.

    Reply
    1. AhNotepad

      Dr John Campbell should be called into question since he spent months encouraging people to get speared by the experimental “gene therapy” (ref Stephan Oelrich, head of Bayer Pharmaceutical.

      Reply
      1. tonyp

        “called into question” ? So, you with your cocksure certainties are to be the judge? I recall a biblical reference (I think it was Jesus) to a reformed sinner. Could we not extend our grace
        similarly?

        Reply
        1. AhNotepad

          Ok, so are you letting Campbell be ungracious to Pfizer? Where is the admission of reform by Campbell, and admission he was wrong about jabs? Was he just doing the equivalent of re-tweeting?

          While you appear to be assuming authority from the bible, there is another point made in the book about not taking the Lord’s name in vain. If you have a point, then making it is fair enough, claiming religious authority for it doesn’t seem justifiable.

          Reply
        2. Eggs ‘n beer

          This Jesus? “So he made a whip out of cords, and drove all from the temple courts, both sheep and cattle; he scattered the coins of the money changers and overturned their tables.”

          John 2:15.

          And AhN wasn’t judging, he was questioning. Jesus was also very good at questioning authorities.

          Reply
          1. Steve

            The Bible is an important historical document and has some good stories and philosophies, but is there any evidence that this Jesus chappy ever existed ? Or, is this an early example of the elites (Church, Roman Empire, Council of Nicea) deciding what the narrative for the plebs was going to be ?

          2. Gary Ogden

            Steve: There is good evidence that Jesus of Nazareth actually existed. See, for example, Reza Aslan’s “Zealot: The Life and Times of Jesus of Nazareth.” I am a non-believer, but I find religious scholarship fascinating. It is clear to me that, in contrast to our own self-evaluation, we truly know very little of what there is to know about most everything, and this leads to woefully insufficient humility.

          3. Prudence Kitten

            To anyone with the slightest interest in those stories about Jesus; or to anyone who finds the questions of unpayable debt important; I strongly recommend Michael Hudson’s book “…and Forgive Them Their Debts: Lending, Foreclosure and Redemption from Bronze Age Finance to the Jubilee Year”. https://www.amazon.co.uk/gp/product/B07QGFZ7DW/ref=dbs_a_def_rwt_hsch_vapi_tkin_p1_i1

            Michal Hudson is to finance, economics, and sociology rather as Dr Kendrick is to medicine. He explains everything clearly, in language that anyone can follow easily. His main thesis is that when the Lord’s Prayer says, “And forgive us our debts”, it means exactly that – literally. Debts of money in this world, here and now. Nothing to do with “pie in the sky”. It doesn’t matter if you are religious or not; Dr Hudson’s explanations are supremely convincing, and lead to the conclusion that Jesus was crucified for the same reason as so many honest men since: he was trying to lighten the unbearable load of debt that intentionally makes the rich richer and the poor poorer.

            It’s a long and sometimes challenging read, but it might be one of the most important books you ever read in your life. Dr Hudson’s work is closely linked with that of his friend, the late Dr David Graeber, whose books are also strongly to be recommended. E.g. “Debt : The First 5000 Years” and “Bullshit Jobs”. The latter argues that as many as half of all jobs in our world are unnecessary and do work that is either useless or actually harmful. Those jobs exist to keep ordinary people’s noses to the grindstone so that they have less time to think.

          4. An Italian Australian at the tropics

            Well, of course.

            Isn’t it what they teach at catechism? It was when I was a kid, debts meant exactly that, and the monks were quite clear about the difference between jews and christians about debt and god, not all the nowadays “judeo christian” BS. It’s what the Bible is about, after all.

          5. thecovidpilot

            Steve,

            When you look at the history of the church and the Bible, it is evident that the church was a grassroots movement for the first three centuries of its existence in the face of widespread persecution. There was a certain Roman emperor who searched for and burned many copies of the Bible, beginning 303 AD. Books were quite expensive, yet there were many copies of the Bible prior to the burning. And despite the book burning and ravages of time, we still have many greek manuscripts and other translations (e.g., the Diatessaron in Syriac ca. 170 AD) of the New Testament from early on.

            https://en.wikipedia.org/wiki/List_of_New_Testament_papyri

            Believe or not, but don’t neglect history.

          6. sticky

            Steve, I never could make up my mind about Jesus, until I watched (the first part of) this, several years ago. You might want to start watching it from 4 minutes in.

      2. Prudence Kitten

        On the other hand, we should try to focus on what a person says rather than becoming too preoccupied with his previous errors. After all, which of us has never made a mistake?

        “I say unto you, that likewise joy shall be in heaven over one sinner that repenteth, more than over ninety and nine just persons, which need no repentance”.

        Reply
      3. Jeremy May

        Personally, I didn’t see him advocating the spearing to which you refer. I must have started watching his videos after that.
        I accepted the vaccines based on the fact that I believed they may lessen the severity of symptoms and likelihood of death. Did Dr Campbell say this? I don’t know.

        However, since I started watching his channel he has covered many fascinating topics such as:
        Ivermectin
        Vitamin D
        Natural v Vaccine immunity
        Personalised treatment
        Myocarditis
        ONS Failings
        (The illusion of) Evidence-based medicine
        Child vaccinations
        Vaccine aspiration

        The language and references he uses are carefully chosen. He presents convincing evidence and concludes, ‘I’ll let you (the viewers) decide.’ He doesn’t come straight out and say that Pfizer are crooks or that the WHO are a pile of horse droppings, because he doesn’t need to. In fact, if he did say such things, he would have been silenced many months ago. By walking this delicate tightrope and allowing us to ‘make our ow minds up’, he is still here to offer is thoughts.

        Had he been ‘shut down’, many people would have missed out on valuable information and he would have been restricted to sniping anonymously on somebody else’s blog, where a limited number would hear him and less would care.

        Thankfully his many followers are benefitting.
        Do I believe he’s the be all and end all. No, I don’t. He is just one part of the wider debate, but a valuable one for me.

        Reply
      4. Janet H

        We all have our epiphany moment. I had my final moment of unblinding about Covid summer of 2021. Others are in their silos because of profession, education, culture, etc. and the blindfold may be off later in their process. At least he had one. I know others who had those times after jabs. I was not able to warn my relatives because I didn’t get the real information until they had all gotten them. I had decided to wait and watch. I’m sure you will agree i should not be judged or I shouldn’t judge my relatives for their decisions . Cheers.

        Reply
  37. Marjorie

    I have been an acolyte for a number of years. Medication is for me a last resort. Reading all that Malcolm has suggested and adjusting our life style to improve our long term outcomes has been an interesting journey. It makes sense and it’s backed up by worldwide research. What’s not to like. Love the basic concepts. Socialising, sunshine, gentle exercise, eat food which looks like it is, not the product from a chemical factory. Its easy, pleasant to follow and most important right. Thank you Malcolm. You have worked extremely diligently for us, your grateful readers. We hope the Nobel Prize you.deserve will one day be yours. We all hope that you and your cohort will be rewarded for your valiant efforts to remove the inaccurate and damaging information which currently holds the field. It’s in all our interests that your work is acknowledged.

    Reply
    1. Ruth Baills

      Yes totally agree with all you said. Love Dr Malcolm Kendrick’s approach in his book “The Clot Thickens”.

      Reply
  38. David Bailey

    Malcolm’s bemused first paragraph reminds me of my theory (voiced here once without much interest) that the real people who are responsible for the mess of Big Pharma are the legislators and academic medical science.

    Imagine for a second, a genuinely honest Big Pharma. It would be expected to fund research on a drug to cure X. They labour for years and come up with a candidate molecule – Y. The only problem is that their funds are getting dangerously low, and they really need to sell a lot of Y pretty damn soon. The trials go well until the final, most expensive phase. Then someone finds that more people taking Y die of something or other than those taking a placebo. This raises the prospect that the whole company will go belly up. Everyone will lose their jobs, and various other useful medicines will stop being produced.

    At that point, the temptation to cheat must be massive – they have done their research impeccably, followed all the rules, and are going to be punished for an outcome they could not have predicted.

    In other words, pharmaceutical companies had to cheat over the years to stay afloat!

    I think research companies should be paid for the research they do, but lose the rights to ideas that they come up with. This is analogous to individual researchers who work for a company and simply earn a salary but don’t own any end product. The NHS, or other similar bodies, would then be free to use completely different manufacturing companies to actually make the new drug.

    Academic science is also obviously heavily responsible for modern Big Pharma, because of their stubborn insistence on keeping to failed dogmas – such as the idea that cholesterol causes CVD. Solving that is probably much harder, but paying companies for the research they do, rather than the end product, would help enormously in my opinion.

    Reply
    1. Eggs ‘n beer

      You make some good points. But a genuinely commercial pharmaceutical company would only be developing drugs supported by cash flows from their existing products, and wouldn’t be going belly up because a research project failed. Just like car manufacturers, electronic companies etc. fund their new products from existing sales.

      But with the Covid vaccines this hasn’t applied. The government has funded the research and the pharmaceuticals keep the profits. Acknowledging failure of the vaccines doesn’t put the companies themselves at risk (except Moderna which is a one trick pony), just the super-profits for shareholders with no risk attached.

      Reply
      1. David Bailey

        Eggs’nbeer wrote:
        ” Just like car manufacturers, electronic companies etc. fund their new products from existing sales.”

        I don’t think that is a close analogy. Designs for cars or electronic equipment can be subjected to endless modifications to solve problems on the fly. However, a molecule is a molecule. If you tweak it, you probably have to go through some/most/all of the testing process again from scratch. Minor changes to molecules can have weird effects. My favourite trivial example is
        acetate: harmless.
        mono-fluoroacetate: toxic and has been used for pest control
        trifluoroacetate: much less toxic.

        With one fluorine atom substituted, enzymes that process acetate gobble up mono-fluoroacetate and choke on it. However, trifluoroacetate is ignored because it is too different from acetate.

        Reply
        1. Eggs ‘n beer

          Not really. Look at what Mazda have achieved with SkyActive engines. Or are trying to achieve with HCCI. Pure (i.e. not applied) research, hoping it will be commercial. Not tweaking, but fundamental rewriting of thermodynamic practices. All funded by sales of cars.

          My favourite chemistry analogy is sodium, incredibly reactive, cannot exist in its pure form except in oil, and chlorine, insanely toxic, corrodes almost anything it comes into contact with, absolutely deadly; yet combine them and life cannot exist without salt.

          Reply
          1. David Bailey

            Yes but joining sodium and chlorine together is hardly a minor tweak!

            Drugs are usually larger molecules so it makes more sense to talk about tweaks. Anyway the point I am making, is that a drug is normally composed of a specific molecule (or sometimes a pair of optical isomers as a mixture – e.g. omeprazole – so there is nothing that can be tweaked if problems arise.
            Adding a couple of methyl groups can transform a safe chemical – tryptamine – into a powerful psychedelic – DMT.

    2. Prudence Kitten

      Well said, David! I would only add that if much more effort (not necessarily money) had been put into studying prevention rather than cure, millions of people might not be sick in the first place.

      Needless to say, most governments are going at top speed in the opposite direction: exhorting people to eat more “healthy whole grains” and vegetable oils, and urging them to abandon the healthiest foods such as meat, eggs, and dairy. Warning of the terrible dangers of exposure to sunlight, so that even when there is enough of it people go out wrapped up like mummies…

      If it were not already obvious that any major government effort usually results in the exact opposite of the intended result, their meddling with nutrition would be a massive first step toward proving the point.

      Reply
      1. David Bailey

        Prudence wrote:

        “Well said, David! I would only add that if much more effort (not necessarily money) had been put into studying prevention rather than cure, millions of people might not be sick in the first place.”

        Well I explicitly recognised that part of the problem is with the structure of pharmaceutical companies, but the other half is obviously with academic medical research – or more generally, with academic science full stop.

        Reforming academic science is a tough problem, I agree! Academic medical science isn’t much interested in prevention (except perhaps things like statins that supposedly extend your life with added side-effects.

        Reply
    3. Steve

      David,
      Re: “I think research companies should be paid for the research they do, but lose the rights to ideas that they come up with. “. Isn’t this already the case for a lot of R&D, which is publicly funded and then sold off to the big boys for onward development ? Maybe, the rights to publicly funded research should remain in the hands of the public ?

      Reply
    4. Eric

      If government were to fully fund academic science or if the pharma research companies didn’t have to market their products, this problem would go away, too.

      Reply
      1. thecovidpilot

        “if the pharma research companies didn’t have to market their products”

        Was this a joke?

        There is too little competition among pharma because there are too many big pharma companies and not enough smaller ones and not enough incentive to discover problems with products and adverse events. Maybe figure out a way to reward whistleblowers instead of punishing them. Figure out a way to connect up product liability lawyers with whistleblowers.

        Throwing money at a problem caused a lot of the problems we see now. Revolving door between the “regulators” and pharma. Governments threw money at the “regulators” and pharma captured the “regulators” with salary to “regulator” employees and direct funding of the “regulators.”

        And media publishing were captured and shallow pockets pharma adversaries were discouraged from publishing.

        Maybe it’s time to consider one of Frank Herbert’s ideas–the Bureau of Sabotage.

        Reply
  39. David

    Does anyone think it would help to donate copies of books like ‘Doctoring Data’ to GP waiting rooms? Maybe I’m hopelessly naive and they’d be immediately binned by the practice manager.

    O.T., anyone know a private practitioner in the SW Midlands (roughly where Wales, the Midlands & SW England meet) who can deal with ulcerative colitis? I have a friend (74) who seems to be in poor health and the NHS way seems to be palliatives/drugs. He eats a very healthy diet … well, by UK standards but he needs clear advice from a medic. on what to test for. Recently he’s had abscesses on or nr the pancreas.

    Or there may be NHS practitioners elsewhere with skill in dealing with such cases. But so far he doesn’t seem to have encountered any of them, judging by his deteriorating condition.

    Reply
    1. Prudence Kitten

      Thanks! A serious crime that, for some inexplicable reason, has not been investigated by the police.

      Reply
      1. thecovidpilot

        I think that it will take villagers with pitchforks and torches banging on the prosecutor’s door at midnight before there will be any prosecutions. This means that we have to keep yelling about this crime, which is obvious to anyone who takes a look at it.

        Reply
  40. Eric

    Here’s a study for you to pick apart, Malcolm. Instead of doing an RCT, they did gene analysis to do Mendelian radomization. I doubt that it is so simple that drinking can be reduced to genes, because this totally ignores factors like choice, habits, social and physical environment.

    Reply
  41. thecovidpilot

    I just found this article…it seemed kind of important…

    “Antiphospholipid antibodies and risk of post-COVID-19 vaccination thrombophilia: The straw that breaks the camel’s back?”

    “Highlights

    • The coagulation pathway can be aberrantly activated during COVID-19 and, in rare cases, following COVID-19 vaccination.
    • APL-induced immunothrombosis may be the unifying mechanism underlying COVID-19 and post-COVID-19 vaccination thrombophilia.
    • ·COVID-19 vaccines may trigger de novoproduction of aPLs or induce a full-blown APS in asymptomatic aPL-positive individuals.
    • Screening for aPLs is recommended prior to undergoing COVID-19 vaccination and between two consecutive vaccine doses.”

    https://www.sciencedirect.com/science/article/pii/S1359610121000423

    Reply
  42. Jeremy May

    I found this amusing. Lifted straight from an email from Michael Eades MD.
    Now, allegedly, this is all speculation?? There are a raft of articles debunking the coincidence that ‘the handbag slap’ was all staged. A raft of articles that have managed to spread the word further and wider!
    (Pfizer was a sponsor of the Academy Awards.)

    “Pfizer is giddily popping Champagne over its HUGE win at the Academy Awards this week. Check out this crazy timeline:
    • Between December 2020 and December 2021: VAERS receives over 3,000 reports of vaccine-induced alopecia after first or second dose of Pfizer Covid vaccine.
    • February 2021: Arena Pharmaceuticals begins third round clinical trials for its new drug, Etrasimod, which treats alopecia.
    • December 2021: Pfizer buys Arena Pharmaceuticals for $7 billion. (Arena’s website is gone now, swallowed up by Pfizer; use the Wayback Machine if you go looking.)
    • March 23, 2022: Pfizer issues a press release announcing “Positive Top-Line Results for Phase 3 Trial of Etrasimod” (now called Ritlecitinib).
    • March 27, 2022: The Academy Awards begin, sponsored by Pfizer.
    … Chris Rock makes a joke about Jada Smith’s alopecia at the Academy Awards.
    … Will Smith sissy-slaps Chris Rock on live TV and acts very put out, and says some non-family-friendly stuff, but gets the award anyway. And gets to keep it. And doesn’t have to take anger management.
    … For the next few weeks, corporate media becomes fascinated with alopecia, how it hurts women, and why Jada Smith was so understandably upset about the joke. If only there were a safe and effective treatment! And, everybody’s talking about the Oscars. Bonus.
    I’m not saying Chris and Will faked the slap. Who knows? But it sure was a great night for sponsor Pfizer, a real marketing coup. My gosh, Pfizer is on a roll — it was so lucky that Chris Rock told THAT exact joke, and THAT exact joke made Will Smith mad enough to act out so totally uncharacteristically and coincidentally promoted Pfizer’s new $7B medication that treats a painfully obvious side-effect of its Covid drug. I mean, what are the odds!”

    Reply
  43. Martin Back

    This morning I chatted with a female relative who has a wide circle of friends, mostly ladies of a certain age. She mentioned five people who I know who have either been diagnosed with cancer or had a cancer return, all in the last few weeks. AFAIK, all of them have been double vaxxed with the Pfizer vaccine.

    This has got to be more than coincidence. It lends credence to the theory that the mRNA vaccine damages your immune system which makes you more vulnerable to cancer.

    Reply
    1. Eggs ‘n beer

      Here’s a mechanism by which an important element of the anti-cancer part of the immune system is being turned off.

      https://www.medrxiv.org/content/10.1101/2021.05.03.21256520v1.full-text

      And a moderately readable article on how interferon works.

      https://miningawareness.wordpress.com/2021/10/02/is-there-a-covid-vaccine-cancer-connection-apparent-immuno-suppressive-impacts-of-vaccine/

      But be careful, it’s still not clear whether the mRNA vaccine per se is causing this damage, or whether it’s the spike proteins produced by them. If it’s the spikes, then any other vaccine might cause the same problems. i. e. don’t fall for the “Novavax (only trialled for two months, with an untested new adjuvant) is safer” trick.

      Reply
    1. AhNotepad

      If someone can show a transmission spectrum of radio waves impacting the human body which shows a diminished intensity of radio waves after transmission, that would prove absorption of radio waves in the human body. But I have yet to see such a spectrum. So, no, I don’t think that 5G radiation is a problem.

      Hmmm, why is microwaves, about the frequencies 5G might be using, used for denial of access for battlefields? The problem with radiation is that for current mobie phone networks there are cases of injury, the probability of which increases the nearer the transmitter is, but 5G uses phased array, so getting away from it is not so effective.

      Tetra radios used by the police in the UK was causing injuries.

      Reply
    2. Eggs ‘n beer

      It’s well known that certain spectra are absorbed by water. Including 60GHz, which is a 5G frequency. Please note that the G in 5G stands for “Generation”, fifth generation, while the G in 60GHz is Giga, a billion. Rain can limit our very low wattage 60GHz transmission to 350m rather than 1.5km in the dry. The body is 70% water.

      Simple experiment.

      Take your iPad, Tablet, phone and move slowly away from your wireless router (2.4 or 5GHz).holding the device with your body between it and the router until it drops a bar on the reception. Turn around, so your body isn’t in the way. The bar should reappear.

      The question is not whether the radiation is absorbed, but does it cause any damage? If it is merely the excitation of water molecules causing a minor and totally undetectable heating effect the answer is no. The energy involved is too small. You can get perfectly acceptable reception with as low a one milliwatt. For a comparison your kettle uses two million times more energy, and the sun gives us 750,000 times more energy per square metre.

      Reply
      1. Steve

        The honest answer, I believe, is that we don’t know what the long term impact of exposure to this radiation is.
        The current standards for exposure to nuclear radiation are orders of magnitude lower than they were say 60 years ago, for example.
        It may take a similar timescale to understand the impact, if any, of exposure to microwave radiation.

        Reply
        1. David Bailey

          5G is actually a collection of frequency bands – some below 1 GHz. Right at the top you have 60 GHz but that might not be very useful because oxygen molecules absorb that frequency.

          It is also worth remembering that at still higher frequencies, you have the infrared band andstill it only damages us by thermal effects if it is high power.

          Reply
        2. David Bailey

          Remember that 5G consists of many sub-bands. only the top band is at 60GHz. Also at higher frequencies still you have infrared, which can only hurt you if there is enough energy to burn you.

          Reply
          1. thecovidpilot

            I don’t know the details about 5G frequencies used. Iirc, there is very little absorption by organic molecules in the far infrared, and only by water in the near. The middle infrared is where most organic absorption occurs. The skin will shield us from the middle infrared, I believe.

        3. Prudence Kitten

          Ironically, as no appropriate research can be done for ethical reasons, I believe that the “danger” level of ionising radiation has been set too HIGH. There are a number of arguments, which I shan’t set out in full. But the gist is this: our ancestors evolved in environments with varying levels of natural radiation, some relatively high. There is no sign that this did any of them harm. People living in some of the highest natural radiation hotspots today seem to have slightly better health and life expectancy, if anything. And the wildlife around Chernobyl has been thriving – apparently the absence of humans and their activities far outweighs any harm from radiation.

          Perhaps the underlying principle is that governments and their international organisations tend to be wrong, in whatever direction.

          Reply
      2. SamT108

        Yes, people seem to forget that there is radiation everywhere anyway. Besides the natural solar and galactic sources of the light spectrum including UVA & UVB, micro- gamma- and x-rays, we are completely surrounded by radio waves from radio and television stations regardless of whether you own a set of either. On top of that practically everyone has a mobile phone aka radiation receiver/transmitter in their pocket or at least nearby, and every shopping mall has wifi, most houses with wifi and bluetooth zapping all over the place, the list goes on and on…

        The issue isn’t so much IS IT DANGEROUS but how much exposure is required to trigger imbalance/didease, perhaps?

        Reply
      3. thecovidpilot

        Anything that absorbs strongly also reflects strongly, which means that transmission will be low. That’s basic classical optics. So there won’t be much penetration by wavelengths where absorption is strong. Pretty much skin depth only.

        Reply
          1. thecovidpilot

            The complex index of refraction is composed of a real part (reflectance) and an imaginary part (absorbance) and is governed by the Kramers Kronig relations.

            Just because something reflects strongly doesn’t necessarily imply that it absorbs strongly.

          2. AhNotepad

            That makes your statement saying strong reflectors are strong absorbers a bit like Humpty Dumpty in Alice in Wonderland (or was it Through the Looking Glass)? Radiation in the GHz has a lot more effect than just skin deep.

          3. thecovidpilot

            “That makes your statement saying strong reflectors are strong absorbers a bit like Humpty Dumpty in Alice in Wonderland”

            I never said that. Please stop putting words in my mouth.

            I said that strong absorbers must necessarily also be strong reflectors. Strong reflection doesn’t necessarily imply strong absorption. There is no property of commutativity wrt the refractive index.

          4. AhNotepad

            In which case can I suggest the correct statement would have been that strong absorbers are necessarily strong emitters? This makes sense for radiation, where reflectors is confusing.

        1. Eggs ‘n beer

          Even if we were discussing optical physics here, if light is absorbed then by definition it is not reflected. If an object appears red, it is because all the other visible spectrum wavelengths are being absorbed by the object and only the red is reflected.

          But this isn’t optical physics. This is electromagnetic waves up to one THz (6G). Just as the energy of all the non-red optical wavelengths are absorbed into the object as heat, so the energy of EW can be absorbed as heat if a resonant frequency of the object matches that of the EW. Nor need it be the skin that absorbs it, if there was a particular frequency absorbed by calcium, for example, the bones would absorb it more than the skin, blood or flesh. An optical analogy is glass. A sheet of common glass appears green viewed edge on, due to iron impurities. If these are removed, the glass is clear. Low iron glass is used in solar energy applications (PV and hot water) as it absorbs significantly less energy than common glass.

          Reply
          1. thecovidpilot

            “Even if we were discussing optical physics here, if light is absorbed then by definition it is not reflected. ”

            Going from my rusty physics memory here…

            When a non-polarized electromagnetic wave of a particular frequency impacts an interface between two media with two different dielectric constants, then five different things may occur–1) the wave may be be transmitted, 2) the wave may be reflected, 3) the wave may be absorbed and relected, 4) the wave may be transmitted and reflected, and 5) the wave may be absorbed, reflected, and transmitted.

            Glass is the first case. The mirror is case 2. I hope this answers your question.

            Why must light which is absorbed necessarily also be reflected? It’s because of the complex index of refraction. It’s possible to have a real part for a wavelength (which corresponds to reflection) without an imaginary part for a wavelength (which corresponds to absorption), but it’s impossible to have an imaginary part without a real part.

            On a tangent, I never studied non-linear optics,, so I don’t know the details of NLO and can’t speak to them.

  44. richard wallace

    This is not related but just wanted all followers of Dr. Kendrick site to know I completed my 35th treatment of EECP. It has helped me immensely. Very little angina at this point and I may do it again.

    Reply
      1. richard wallace

        The treatment was 900.00 per session. I paid 40.00$ copayment for per treatment for 35 days which …….1480.00……..L am on medicare advantage plan.

        Reply
        1. jeresavo1

          $36k all in all – $900 seems to be expensive for what appears to be a squeeze on the legs using fabric.
          Can I ask how long each session lasted ?

          Reply
          1. richard wallace

            yes i agree it’s a lot but not having any angina right now is well worth it. Each session lasts 1 hour…….Mostly laying on bed listening to music……and watching Dr. K and others on youtube…. and thats what it is….large blood pressure type cuffs sqeezing your calfs and thighs….but it worked for me…..however did not help PAD pain (calf and leg) very much….changed it a little bit

  45. Martin Back

    FDA vs. WHO

    https://www.fda.gov/media/137574/download
    Q. Is Veklury (remdesivir) approved by FDA to treat COVID-19?
    A. On October 22, 2020, FDA approved the new drug application (NDA) 214787 for Veklury (remdesivir) for use in adults and pediatric patients (12 years of age and older and weighing at least 40 kg) for the treatment of COVID-19 requiring hospitalization

    But a month later…

    https://www.who.int/news-room/feature-stories/detail/who-recommends-against-the-use-of-remdesivir-in-covid-19-patients
    20 November 2020
    WHO has issued a conditional recommendation against the use of remdesivir in hospitalized patients, regardless of disease severity, as there is currently no evidence that remdesivir improves survival and other outcomes in these patients.

    This recommendation, released on 20 November, is part of a living guideline on clinical care for COVID-19. It was developed by an international guideline development group, which includes 28 clinical care experts, 4 patient-partners and one ethicist.

    Eff the WHO, let’s spend money…

    https://scitechdaily.com/covid-19-treatment-remdesivir-dominated-hospital-drug-spending-in-2021/
    The COVID-19 treatment remdesivir dominated hospital drug spending in 2021, accounting for nearly 10% of all pharmaceutical expenses and outpacing the next three drugs combined, according to the ASHP (American Society of Health-System Pharmacists) National Trends in Prescription Drug Expenditures and Projections for 2022.

    Reply
  46. Janet H

    Remdisivir almost murdered my SIL plus the vent October 2021. Her hubby, my brother was completely out of the process and not allowed access in any way. They could do anything they wanted to her in the hospital without any permission papers signed. She was unconscious. She has lost any memory of 2 weeks. She barely survived. 60 yo.

    Reply
    1. Prudence Kitten

      In theory, before the UK government gives up our most cherished freedoms to an unelected and utterly unanswerable overseas power, it must consult widely with the citizens and Parliament. However in Step 1 citizens and Parliament were terrorised and conditioned to cower at home, keeping their heads down. So now our unelected dictatorship in London can carry on merrily establishing the World Reich while citizens fuss about unauthorised parties.

      Reply
      1. AhNotepad

        It is people who think they give up their freedoms. If they stopped doing that, the tyrants would be unable to operate. The freedoms are inalienable rights, and they cannot be given up. If people think otherwise, the tyrants win their fraud game.

        Reply
  47. jeresavo1

    Sometimes we might forget how we are ourselves are to blame for stirring up demand for a magic solution to our real and imagined med issues . Many years ago, possibly 1970’s, i came across my mother with her sisters having a morning tea & busily swapping tablets. Their own doctors were obviously denying them in some shape or fashion – so it was up to these ladies to right that wrong and swap the smarties.

    Reply
  48. john

    Been reading Dr. K’s The Clot Thickens. What are his thoughts about PCSK9 genomic testing and the many mutations that can exist; some of which are tied to higher LDL (gain of function) vs lower LDL (loss of function). There have been studies that seem to point towards higher CVD and MIs depending on the mutant gene. The conclusions from these studies are all the same, in that mutations in this gene that impacts LDL levels are responsible for increased CVD risk. Is this just another example of “yellow fingers” and that correlation does not mean causation?

    Reply
    1. David Bailey

      I am reminded of a study that showed that rats fed a high saturated fat diet developed more CVD.

      This looked significant until someone pointed out that the specific strain of rats used in the experiment had been bred to be sensitive to saturated fat!

      It would seem you simply cannot assume that the researchers have done due diligence!

      Sorry, I don’t have the link.

      Reply
    1. Eggs ‘n beer

      The effects of vaccines in reducing immune responses has been long established, e.g.

      https://www.nejm.org/doi/full/10.1056/NEJM199605093341903

      This is probably why Astra Zeneca used the quadrivalent MenACWY meningitis vaccine as the ‘placebo’ in the control arm of most of their Covid vaccine trials. It guarantees that you’ll get increased infections (and even a couple of deaths, bonus!) in the non-covid-vaccinated part of the trial. In the small AZ South African trial, where saline solution was used instead, infection rates were equal.

      Vaccines are designed to trick your immune system. There should be no presumption that they will only trick it in positive ways. Or that tricking the system to provide extra protection against a particular bug won’t be at the expense of lower immunity against others.

      Reply
      1. AhNotepad

        This appears to be the reason so many people in the US have peanut allergies. Because vaccines hyper-stimulate the immune response, a response is trigged to the components in the vaccine. Since peanut oil was used in some vaccines, victims encountering it later had a heightened reaction.

        Reply
      2. Steve

        My fire fighting analogy is that a vaccine is like a ‘super squirter’, and natural immunity is like a fire blanket. If you want to put a fire out then a fire blanket will kill it dead. A ‘super squirter’ just extinguishes a very small part of the blaze for a very small time, and then it gets worse.
        However, in line with Dr K’s article on ‘Don’t just do something, stand there’, the incompetent, corrupt, liars that apparently govern the UK must do something. So a vaccine, whether it works or not, is the perfect tick in the box. Natural immunity is a ‘no, no’ and an admission that politicians/experts and Doctors are not omnipotent. The public cannot be exposed to this heresy.

        Reply

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